Fig. 1

Removing D2Rs from iMSNs promoted avoidance in exploratory tasks. a Path plots for control and iMSN-Drd2KO mouse in the zero maze. b Time in open arms, c movements into the open arms, and d movements into the closed arms for iMSN-Drd2KO, CIN-Drd2KO, and DAT-Drd2KO mice. e Correlation between time in open arms and number of movements into the open for iMSN-Drd2KO mice. f–j Same presentation as (a–e), but for open field data. Circles reflect individual mice, lines are linear regressions. *s denote significance between control and iMSN-Drd2KO by Sidak’s post hoc test following 2-way ANOVA