Fig. 3

Optogenetic stimulation of iMSNs promoted avoidance of open areas. a Example movement traces on zero maze during optogenetic stimulation. b Time in open arms, c movements into the open arms, and d movements into the closed arms for control and iMSN-ChR2 mice. e Correlation between time in open arms and number of movements into the open during LED ON for iMSN-ChR2 mice. f–j Same data format as (a–e) but for open field. Black lines reflect paired comparison for individual mice, red lines are linear regressions. *s denote significance between control and iMSN-Drd2KO by Sidak’s post hoc test following two-way ANOVA