Fig. 2
From: An integrated analysis of genes and functional pathways for aggression in human and rodent models
IPA network analysis of the 40 top-ranked genes. Network A is involved in behavior, nervous system development and function, and cell-to-cell signaling and interaction (score 35, 15 genes). Network B is involved in neurological disease, psychological disorders, nervous system development and function (score 29, 13 genes). Network C is involved in organismal functions, cellular function and maintenance, small molecule biochemistry (score 26, 12 genes). Genes highlighted in color correspond to the 40 top-ranked genes. In purple, human-only aggression genes (from GWAS and OMIM studies), in blue, rodent-only aggression genes (rodent model transcriptomic genes and KO mice genes), and in orange, genes from both human and rodent studies.
