Table 3 Canonical pathways shared by all three categories of genes
From: An integrated analysis of genes and functional pathways for aggression in human and rodent models
Canonical pathways | Human GWAS genes | Rodent transcriptome genes | Causal genes |
|---|---|---|---|
Signaling by Rho family GTPases | 2.294 | 1.594 | 1.847 |
ERK/MAPK signaling | 2.093 | 2.238 | 2.965 |
G-protein-coupled receptor signaling | 1.999 | 3.971 | 9.286 |
Axonal guidance signaling | 1.947 | 1.714 | 2.499 |
Reelin signaling in neurons | 1.939 | 1.759 | 1.432 |
Molecular mechanisms of cancer | 1.647 | 2.591 | 3.075 |
Gαs signaling | 1.609 | 2.054 | 5.589 |