Fig. 4 | Molecular Psychiatry

Fig. 4

From: The neuropathology of bipolar disorder: systematic review and meta-analysis

Fig. 4

Meta-analysis of neuronal density in lateral, basal and accessory basal nuclei of the amygdala. Meta-analysis of Berretta et al. [53] and Bezchlibnyk et al. [54]. For the accessory basal nucleus, we combined data from parvocellular and magnocellular subnuclei reported in [54]. Neuronal density is reduced in BD in the lateral nucleus (SMD −0.81, p = 0.008), basal nucleus (SMD −0.85, p = 0.005) and accessory basal nucleus (SMD −0.97, p = 0.002). SMDs should be interpreted taking into account the fact that ref. 53 used 3D counting (neurons per unit volume) whereas ref. 54 used 2D counting (neurons per unit area)

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