Table 4 Parametric survival model, with Weibull hazard distribution, for incident EDS vs. baseline ICS, HANDLS 2004–2013

From: Systemic inflammation is associated with depressive symptoms differentially by sex and race: a longitudinal study of urban adults

 

Nb

nb

Tb

Hazard Ratio

(95% CI)

P

ICS

      

All

796

185

3,621

1.15

(0.99–1.34)

0.068

Men

348

66

1,605

1.11

(0.86–1.43)

0.44

Women

448

119

2,017

1.20

(0.98–1.47)

0.073

Whites

330

83

1,450

1.10

(0.86–1.41)

0.45

African-Americans

466

102

2,171

1.28

(1.04–1.56)

0.017

  1. CES-D Center for Epidemiologic Studies-Depression scale, HANDLS healthy aging in neighborhoods of diversity across the lifespan, HS high school, ICS inflammation composite Score, n3 omega-3, n6 omega-6, PUFA polyunsaturated fatty acids, SEE standard error of the estimate
  2. aModels were further adjusted for other covariates. Covariates considered as potential confounders included: baseline age was centered at 50 y, sex, race, PIR, education, employment status, total energy intake centered at 2000kcal/d, total carotenoid intake at 3 mg/1,000 kcal/d, vitamin C intake at 30 mg/1,000 kcal/d, vitamin A intake at 300 RE/1,000 kcal/d, vitamin E at 3 mg/1,000 kcal/d, vitamin B-6 at 0.8 mg/1,000 kcal/d, vitamin B-12 at 3 μg/1,000 kcal/d, folate at 170 μg/1,000 kcal/d, n-3 PUFA:n-6 PUFA at 0.11. Healthy Eating Index-2010 was centered at 42, body mass index at 30, co-morbid conditions (diabetes, hypertension, dyslipidemia, CVD, inflammatory conditions) and use of NSAIDs. Models stratified by sex or race excluded those covariates
  3. bN = number of subjects, n = number of failures, T = time at risk (Person-years)
  4. Bold values are for P < 0.05. Bold and italic values are for P < 0.10