Fig. 2 | Molecular Psychiatry

Fig. 2

From: Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease

Fig. 2

Results from phenome-wide association studies of polygenic scores for MDD (a) and loneliness (b) in BioVU. The red line denotes the Bonferroni threshold for statistical significance (0.05/882 = 5.67 × 10−5), and phenome-wide significant phecodes are labeled. Upward triangles indicate increased odds for a given phecode per 1-SD increased risk in the polygenic score, while downward triangles indicate reduced odds of a given phecode. Interactive plots can be viewed at: https://sealockj.shinyapps.io/mdd_loneliness_cad_interactive/

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