Fig. 3: Correlations between 5-HTT availability and performance in behavioral phenotype assessments.
From: Serotonin transporter availability in adults with autism—a positron emission tomography study
Spearman correlation coefficient (rs). GM total gray matter, NEOC neocortex, FC frontal cortex, OC occipital cortex, PC parietal cortex, TC temporal cortex, OFC orbitofrontal cortex, rMFC rostral middle frontal cortex, FFC fusiform cortex, INS insular cortex, ACC anterior cingulate cortex, PCC posterior cingulate cortex, AMG amygdale, HIP hippocampus, NAc nucleus accumbens, CAU caudate, PUT putamen, PAL pallidum, THA thalamus, and BS brainstem. Reading the mind in the eye (EYE), movie for assessment of social cognition (MASC), Faux Pas, verbal fluency letter production (VF lp), verbal fluency category production (VF cp), verbal fluency semantic flexibility (VF sf), tower test (Tower), Conner’s continuous performance test (CPT), embedded figure test (EFT), and fragmented picture test (FPT). In tests Tower, EFT, and FPT, a higher score is indicative of lower performance. For visualization purposes, the sign of rs for these tests has been changed in the figure to reflect the positive relationship between 5-HTT availability and cognitive performance (*p < 0.05, **p < 0.01, ***p < 0.001, uncorrected for multiple comparisons).
