Table 1 Summary of most relevant autoantibody-antigen reactivity combinations that are 100% specific with an ASD diagnosis in training and validation sets.
From: Risk assessment analysis for maternal autoantibody-related autism (MAR-ASD): a subtype of autism
Patterns | ASD + training set n (%) | TD + training set n (%) | Fisher exact p value | ASD + validation set n (%) | TD + validation set n (%) | Training/validation precision (%) | Fisher exact p value |
|---|---|---|---|---|---|---|---|
CRMP1 + GDA | 15 (7) | 0 (0) | 0.0002 | 4 (2) | 0 (0) | 100 | 0.1443 |
CRMP1 + CRMP2 | 12 (6) | 0 (0) | 0.0007 | 4 (2) | 0 (0) | 100 | 0.1443 |
NSE + STIP1 | 8 (4) | 0 (0) | 0.0093 | 6 (2) | 0 (0) | 100 | 0.0435 |
CRMP2 + STIP1 | 6 (3) | 0 (0) | 0.0346 | 3 (1) | 0 (0) | 100 | 0.2693 |
GDA + YBOX | 5 (2) | 0 (0) | 0.0669 | 1 (0) | 0 (0) | 100 | 1 |
CRMP2 + GDA | 4 (2) | 0 (0) | 0.1303 | 1 (0) | 0 (0) | 100 | 1 |
CRMP2 + NSE | 4 (2) | 0 (0) | 0.1303 | 3 (1) | 0 (0) | 100 | 0.2693 |
LDHA + NSE + STIP1 | 3 (1) | 0 (0) | 0.2553 | 1 (0) | 0 (0) | 100 | 1 |
CRMP1 + GDA + LDHB | 3 (1) | 0 (0) | 0.2553 | 1 (0) | 0 (0) | 100 | 1 |
CRMP2 + YBOX | 3 (1) | 0 (0) | 0.2553 | 2 (1) | 0 (0) | 100 | 0.5129 |
CRMP1 + NSE + STIP1 | 3 (1) | 0 (0) | 0.2553 | 2 (1) | 0 (0) | 100 | 0.5129 |
CRMP1 + CRMP2 + NSE | 3 (1) | 0 (0) | 0.2553 | 1 (0) | 0 (0) | 100 | 1 |
