Fig. 1: Volume of distribution (VT) values of [11C]Ro15-4513 in the hippocampus by group for antipsychotic-free patients (with mean ± SD).

There was significantly lower [11C]Ro15-4513 volume of distribution (VT) in the hippocampus in antipsychotic-free patients with schizophrenia relative to healthy controls (*p < 0.05; effect size = 1.4). Group average VT parametric maps showing sagittal, coronal, and transverse images (from left to right) for: b healthy controls and c antipsychotic-free schizophrenia patients.