Table 1 A. Effects of pre-and postsynaptic localized SHANK2A and SHANK2A(R462X) overexpression in transgenic mice. B. Schematic representations of the distribution of synapses enriched for Ca²⁺-permeable (in green; high conductance) or Ca²⁺-impermeable (in orange; low conductance) AMPARs in apical and basal dendrites of hippocampal CA1 pyramidal cells in wild-type, SHANK2A overexpressing (SH-WT) and SHANK2A(R462X) overexpressing (SH-RX) mice.

From: Imbalanced post- and extrasynaptic SHANK2A functions during development affect social behavior in SHANK2-mediated neuropsychiatric disorders