Fig. 1: Overview of topmost implicated plasma proteins of the complement and coagulation pathways identified in two or more studies. | Molecular Psychiatry

Fig. 1: Overview of topmost implicated plasma proteins of the complement and coagulation pathways identified in two or more studies.

From: Dysregulation of complement and coagulation pathways: emerging mechanisms in the development of psychosis

Fig. 1: Overview of topmost implicated plasma proteins of the complement and coagulation pathways identified in two or more studies.

Number of studies showing altered complement proteins in A longitudinal conversion and CHR-transition studies, B longitudinal general population studies of the ALSPAC cohort, C case-control psychosis studies, and D case-control psychosis spectrum studies. Number of studies showing altered coagulation proteins in E longitudinal conversion and CHR-transition studies, F longitudinal general population studies of the ALSPAC cohort, G case-control psychosis studies, and H case–control psychosis spectrum studies. Positive or negative depiction indicates direction of fold change found in each study, e.g., a mention of −2 means that two studies found this protein to be downregulated, threshold indicated as two studies.

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