Fig. 1: Map of associations of regional brain asymmetries with polygenic risks for ASD and schizophrenia.

Loadings of regional brain asymmetries derived from canonical correlation analyses with ASD (A) and schizophrenia (B) polygenic risk scores. A positive loading (red) for a given region indicates a leftward shift of asymmetry associated with increased polygenic risk. Conversely, a negative loading (blue) indicates a rightward shift of asymmetry associated with increased polygenic risk.