Fig. 3: Meta-analyses of thalamic D2-R availability differences between patients and controls.

A Patients show significantly overall lower D2-R levels in whole thalamus compared with healthy control subjects. B Meta-analysis only including studies which used the two high-affinity radioligands [11C]FLB457 and [18F]Fallypride. Additional meta-analyses excluding studies with partially overlapping samples, and funnel plots can be found in the supplementary information.