Fig. 4: Analyses stratified by sex.

A Surface rendering of p value maps, for the interaction between CSF Aβ42/40 and APOE-ε4, as well as age, separately for women and men in the ALFA sample. B, C Group scatterplots, stratified by sex, of the assessed interactions in regions of interest. D Same as in A, in the ADNI sample. E, F Same as in B and C, in the ADNI sample. Wε4+ Women APOE-ε4 carriers, Wε4− Women APOE-ε4 non-carriers, Mε4+ Men APOE-ε4 carriers, Mε4− Men APOE-ε4 non-carriers.