Table 4 Structural comparison between Human Developing Neurons (HDNs) and Monocyte-derived-neuronal-like cells (MDNCs) after treatment with colchicine.

From: Dopamine-induced pruning in monocyte-derived-neuronal-like cells (MDNCs) from patients with schizophrenia

Structural Parameter

HDNsa

P value

MDNCsa

P value

Control

Colchicine

Control

Colchicine

LPN

0.99 ± 0.004

0.848 ± 0.023

<0.00001

0.943 ± 0.019

0.756 ± 0.035

0.0067

LSN

0.859 ± 0.086

0.706 ± 0.053

0.05

1.2 ± 0.022

1.09 ± 0.026

0.019

Primary Neurites

1 ± 0.00

0.997 ± 0.003

0.75

1.03 ± 0.006

1.11 ± 0.084

0.88

Secondary Neurites

0.951 ± 0.021

0.859 ± 0.042

0.12

1.03 ± 0.032

0.74 ± 0.064

0.008

All Neurites

0.99 ± 0.004

0.96 ± 0.008

0.04

1.03 ± 0.019

0.89 ± 0.06

0.03

  1. aData are expressed as ratios.
  2. LPN longest primary neurite, LSN longest secondary neurite.
Back to article page