Table 1 Description of baseline characteristics of the 3 cohort samples.

From: Corticolimbic DCC gene co-expression networks as predictors of impulsivity in children

MAVAN

Sample description

Total (n = 202)

Low ePRS (n = 96)

High ePRS (n = 106)

p-value

Sex – male (n)

49.5% (100)

56.3% (54)

43.4% (46)

0.09

Maternal age at birth (years)

30.72 (4.90)

31.42 (5.07)

30.08 (4.67)

0.053

Gestational age (weeks)

39.03 (1.23)

38.89 (1.30)

39.16 (1.15)

0.11

Birth weight (g)

3313 (452)

3300 (450)

3224 (456)

0.71

Maternal education – University degree or above

55.7% (108)

54.3% (50)

56.9% (58)

0.47

Low family income

20.6% (50)

25.8% (23)

27.3% (27)

0.96

GUSTO

Sample description

Total (n = 398)

Low ePRS (n = 202)

High ePRS (n = 196)

p-value

Sex – male (n)

53.3% (212)

49.5% (100)

57.1% (112)

0.15

Maternal age at birth (years)

31.55 (5.04)

31.81 (5.34)

31.28 (4.73)

0.37

Gestational age (weeks)

38.49 (1.28)

38.47 (1.33)

38.50 (1.23)

0.87

Birth weight (g)

3137 (416)

3127 (441)

3147 (391)

0.39

Maternal education – University degree or above

35.64% (103)

38.36% (56)

32.88% (47)

0.39

Household income < $2000 SGD per month

12.11% (35)

15.75% (23)

8.39% (12)

0.08

ALSPAC

Sample description

Total (n = 4392)

Low ePRS (n = 2210)

High ePRS (n = 2182)

p-value

Sex – male (n)

49.2% (2159)

48.6% (1075)

49.7% (1084)

0.51

Maternal age at birth (years)

29.31 (4.47)

29.31 (4.47)

29.31 (4.47)

0.97

Gestational age (weeks)

39.76 (1.27)

39.79 (1.26)

39.73 (1.28)

0.11

Birth weight (g)

3499 (465)

3503 (458)

3496 (471)

0.61

Maternal education – University degree or above

18.9% (786)

19.7% (411)

18.2% (375)

0.25

Low SESa

35.0% (1537)

34.5% (762)

35.5% (775)

0.49

  1. Continuous variables are expressed as mean (SD); categorical variables are expressed as percentage (number of subjects).
  2. aWe used “crowding index” as a proxy measure for SES. This index was calculated by dividing the number of individuals living in the family’s residence, by the number of rooms in the residence, and we considered low SES when crowding index > 0.75, and high SES when crowding index = 0.75.