Fig. 1: Immune system mutations have a highly heterogeneous effect on mouse brain anatomy.

A Nearly all brain structures showed a significant effect of strain evaluated using F-statistics from ANOVA. B The directional effect in females of the various mutant strains relative to the wild-type strains is visualised using t-statistics and shows a heterogeneous neuroanatomical phenotype. Regions larger or smaller in mutants relative to wild-type are given maroon-pink and blue-turquoise colours, respectively, if effects are <5% FDR. Saturated colours represent effects <0.01% FDR.