Fig. 1: Dropout effect in single-cell transcriptome analysis. | Molecular Psychiatry

Fig. 1: Dropout effect in single-cell transcriptome analysis.

From: Introducing the brain erythropoietin circle to explain adaptive brain hardware upgrade and improved performance

Fig. 1

a Unbiased clustering of hippocampal cells from mice under normoxia (n = 2) or hypoxia (n = 2), represented in UMAP space, reveals 16 distinct cell populations across conditions [77]. b The extremely low expression of EPOR in these populations, compared to the abundant expression of renin receptor (c), illustrates the partial ‘dropout effect’ of scRNA-seq for EPOR. We note that EPO is not detectable at all using this method.

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