Fig. 1: APOE ε4 augments the odds for AD independently conferred by brain iron. | Molecular Psychiatry

Fig. 1: APOE ε4 augments the odds for AD independently conferred by brain iron.

From: Apolipoprotein E potently inhibits ferroptosis by blocking ferritinophagy

Fig. 1

Iron levels in post-mortem inferior temporal cortex from 608 donors from the MAP study. Of these subjects, 230 had a clinical and pathological diagnosis of AD, and 378 were negative under these criteria. A Iron levels in subjects stratified by diagnosis and ε4 status. B Logistic regression curves for predicting diagnosis, stratified by ε4 status.

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