Table 2 Descriptive characteristics of the EMA study population.

From: Maternal autoantibody profiles as biomarkers for ASD and ASD with co-occurring intellectual disability

 

ASD

ID

GP

ASD vs GP

ASD vs ID

ID vs GP

N = 540

N = 184

N = 420

   

N (%)

N (%)

N (%)

χ2 p value

χ2 p value

χ2 p value

Maternal age

   

0.08

<0.001

<0.001

  <20

17 (3.15%)

26 (14.13%)

21 (5.0%)

   

  20–24

80 (14.81%)

41 (22.28%)

70 (16.67%)

   

  25–29

146 (27.04%)

51 (27.72%)

129 (30.71%)

   

  30–34

196 (36.3%)

43 (23.37%)

145 (34.52%)

   

  >=35

101 (18.7%)

23 (12.5%)

55 (13.1%)

   

Maternal race

   

0.20

<0.001

0.01

  White

399 (73.89%)

160 (86.96%)

334 (79.52%)

   

  Asian

109 (20.19%)

11 (5.98%)

65 (15.48%)

   

  Other

27 (5.0%)

12 (6.52%)

19 (4.52%)

   

  Missing

5 (0.93%)

1 (0.54%)

2 (0.48%)

   

Maternal ethnicity

   

0.14

<0.001

<0.001

  Hispanic

220 (40.74%)

128 (69.57%)

198 (47.14%)

   

  Not Hispanic

315 (58.33%)

55 (29.89%)

219 (52.14%)

   

  Missing

5 (0.93%)

1 (0.54%)

3 (0.71%)

   

 Parity

   

0.02

0.005

0.30

  Multiparous

294 (54.44%)

122 (66.3%)

260 (61.9%)

   

  Primiparious

246 (45.56%)

62 (33.7%)

160 (38.1%)

   

Maternal birth country

   

0.05

<0.001

<0.001

  US

267 (49.44%)

83 (45.11%)

203 (48.33%)

   

  Mexico

130 (24.07%)

84 (45.65%)

127 (30.24%)

   

  Other

143 (26.48%)

17 (9.24%)

90 (21.43%)

   

Maternal education

   

0.01

<0.001

<0.001

  <High School

98 (18.15%)

78 (42.39%)

102 (24.29%)

   

  High School Grad

114 (21.11%)

47 (25.54%)

112 (26.67%)

   

  Undergrad College

220 (40.74%)

46 (25.0%)

144 (34.29%)

   

  Post-Grad College

100 (18.52%)

11 (5.98%)

59 (14.05%)

   

  Unknown

8 (1.48%)

2 (1.09%)

3 (0.71%)

   

Child characteristics

  Child Sex

   

0.62

<0.001

<0.001

   Male

442 (81.85%)

102 (55.43%)

349 (83.1%)

   

   Female

98 (18.15%)

82 (44.57%)

71 (16.9%)

   

Birth type

   

0.33

0.93

0.39

  Singleton

526 (97.41%)

179 (97.28%)

413 (98.33%)

   

  Multiple

14 (2.59%)

5 (2.72%)

7 (1.67%)

   

Birth weight

   

0.10

<0.001

<0.001

  <1500 g

5 (0.93%)

14 (7.61%)

6 (1.43%)

   

  1500–2499 g

37 (6.85%)

25 (13.59%)

16 (3.81%)

   

  >=2500 g

498 (92.22%)

145 (78.8%)

398 (94.76%)

   

Gestational age

   

0.92

<0.001

<0.001

  <32 weeks

11 (2.04%)

16 (8.7%)

9 (2.14%)

   

 33–36 weeks

41 (7.59%)

26 (14.13%)

29 (6.9%)

   

  >=37 weeks

488 (90.37%)

142 (77.17%)

382 (90.95%)

   
  1. Demographic differences between groups was calculated by χ2 test and p values > 0.05 were bolded and considered significant.
  2. ASD Autism Spectrum Disorders, ID intellectual disability, GP general population.