Table 2 Summary statistics by high and low whole-brain WML volume groups.

From: Rest-activity rhythms and tract specific white matter lesions in older adults at risk for cognitive decline

 

High

Low

p value

Clinical characteristics

  n

54

54

-

  Age (years)a

73.52 (7.63)

64.19 (7.60)

<0.001

  Sex, female (%)b

32 (59.26)

31 (57.41)

1.000

  Scan type, 2D (%)b

25 (46.30)

15 (27.78)

0.073

  MMSEc

29.00 [29.00,30.00]

29.00 [28.00,30.00]

0.300

  GDS-15c

2.00 [0.00,4.00]

2.00 [1.00,4.00]

0.526

  PSQI total scorea

6.39 (3.68)

6.86 (3.86)

0.530

  BMIc

27.30 [24.96,30.60]

25.00 [21.99,29.43]

0.030

  Antidepressants (%)b

13 (24.07)

11 (20.75)

0.857

  CIRS-Gc

5.00 [3.00,6.00]

3.00 [2.00,6.00]

0.063

  Vascular risk index, (%)d

  

0.813

   0

18 (37.50)

19 (35.85)

 

   1

16 (33.33)

22 (41.51)

 

   2

11 (22.92)

9 (16.98)

 

   3

3 (6.25)

3 (5.66)

 

Actigraphy derived measures

  Total sleep time (min)

424.67 (69.61)

448.57 (56.59)

0.055

  WASO (min)

54.34 (43.98)

46.04 (32.27)

0.266

  Inter-daily stability

0.51 (0.13)

0.55 (0.12)

0.093

  Intra-daily variability

0.83 (0.22)

0.78 (0.22)

0.215

  Relative amplitude

0.89 [0.83,0.93]

0.91 [0.86,0.94]

0.078

  L5

7.21 [4.32,11.91]

6.12 [4.33,9.02]

0.291

  M10

124.02 (47.77)

135.53 (47.14)

0.210

  L5 start time (24-h)

1477.00 (86.41)

1457.07 (53.65)

0.153

  1. Mean (SD) unless otherwise indicated; Median [IQR].
  2. MMSE Mini-Mental State Examination, GDS-15 Geriatric Depression Scale-15 item, BMI Body Mass Index, CIRS-G Cumulative Illness Rating Scale-Geriatric version, WASO Wake After Sleep Onset, L5 Mean activity during least active 5-h period, M10 Mean activity during most active 10-h period, WML White matter lesions.
  3. aT-test.
  4. bChi-square test.
  5. cKruskal–Wallis test.
  6. dFisher’s exact test.
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