Table 1 Characteristics of the cohort.

Age (years)

84.9 ± 4.27

85.4 ± 4.08

84.4 ± 4.44

85.5 ± 4.26

82.7 ± 3.67^a

Sex (F/M)

58/17

25/10

33/7

43/14

15/3

Education (years)

14.2 ± 2.98

15.1 ± 3.17

13.3 ± 2.55

14.3 ± 3.18

13.9 ± 2.26

MMSE (/30)

28.8 ± 1.24

29 ± .93

28.6 ± 1.41

28.8 ± 1.13

28.7 ± 1.53

ACE-R total (/100)

92.68 ± 4.91

93.11 ± 4.35

92.3 ± 5.39

92.6 ± 4.86

92.9 ± 5.21

ACE-R Memory (/26)

23.2 ± 2.83

23.1 ± 2.71

23.3 ± 2.95

23.2 ± 2.97

23.2 ± 2.39

CERAD Delayed (/10)

8.15 ± 1.54

7.83 ± 1.63

8.43 ± 1.41

8.18 ± 1.53

8.06 ± 1.58

RAVLT Delayed (/15)

10.6 ± 3.32

10.2 ± 3.39

11.0 ± 3.25

10.7 ± 3.21

10.4 ± 3.72

RCFT Delayed (/36)

14.9 ± 6.17^b

15.0 ± 5.24

14.8 ± 6.95

14.0 ± 5.78

17.6 ± 6.7^a

p-tau181 (pg/ml; n = 73)

16.3 ± 5.64

14.7 ± 5.14

17.7 ± 5.72^c

15.8 ± 5.82

17.9 ± 4.79

n (%)

n (%)

n (%)

n (%)

n (%)

Aβ+ (>29 CL\1.48 SUVR)

40 (53.3)

35 (46.7)

40 (53.3)

26 (45.6)

14 (77.8)

APOE4−

57 (76)

31 (88.6)

26 (65)

57 (100)

–

APOE4+

18 (24.3)

4 (11.4)

14 (35)

–

18 (100)

APOE E2/E4

3 (4.1)

1 (2.9)

2 (5)

–

3 (16.7)

APOE E3/E4

14 (19.2)

3 (8.6)

11 (27.5)

–

14 (77.8)

APOE E4/E4

1 (1.4)

–

1 (2.5)

–

1 (5.6)

Middle-old (78–84 years)

38 (50.7)

15 (42.9)

23 (57.5)

25 (43.9)

13 (72.2)

Oldest-old (≥85 years)

37 (49.3)

20 (57.1)

17 (42.5)

32 (56.1)

5 (27.8)