Fig. 3: Structural and functional locus coeruleus (LC) whole-brain connectivity showed a linear relationship (Pearson’s r = 0.687, p = 0.001). | Molecular Psychiatry

Fig. 3: Structural and functional locus coeruleus (LC) whole-brain connectivity showed a linear relationship (Pearson’s r = 0.687, p = 0.001).

From: In vivo tractography of human locus coeruleus—relation to 7T resting state fMRI, psychological measures and single subject validity

Fig. 3

Big circles represent mean connectivity values to each brain region (right and left hemisphere) whilst small symbols illustrate connectivity on the individual subject level (e.g., two small red triangles represent LC connectivity to the right and left thalamus for one subject). This association is driven by regions with both high structural and functional connectivity, which reveals that brain areas with high structural connectivity to the LC are also tightly functionally linked to the LC in the resting state, e.g., the thalamus or ventral diencephalon.

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