Table 1 Subjects demographics.
From: A predictive ensemble classifier for the gene expression diagnosis of ASD at ages 1 to 4 years
Training set | Test set | |||||
|---|---|---|---|---|---|---|
ASD | TD | ASD vs TD p value | ASD | TD | ASD vs TD p value | |
Number of Subjects | 93 | 82 | 0.406 | 34 | 31 | 0.71 |
Age of last Visit in | 50.8 ± 28.8 | 34.5 ± 8.4 | <0.001 | 47.4 ± 28.0 | 39.2 ± 15.3 | 0.144 |
months | ||||||
Mullen Scales of Early Learning | ||||||
Visual Reception | 40.1 ± 13.3 | 60.3 ± 10.9 | <0.001 | 38.8 ± 15.4 | 55.1 ± 9.2 | <0.001 |
Fine Motor | 34.8 ± 11.4 | 54.4 ± 9.5 | <0.001 | 36.9 ± 13.9 | 52.8 ± 8.9 | <0.001 |
Receptive Language | 32.2 ± 13.1 | 53.3 ± 8.1 | <0.001 | 29.0 ± 16.6 | 52.4 ± 7.6 | <0.001 |
Expressive Language | 30.7 ± 15.8 | 54.4 ± 9.6 | <0.001 | 28.5 ± 16.8 | 49.8 ± 8.1 | <0.001 |
Early Learning Composite | 73.6 ± 18.5 | 111.1 ± 13.3 | <0.001 | 71.9 ± 21.0 | 105.0 ± 11.1 | <0.001 |
Vineland Adaptive Behavior Scales | ||||||
Communication | 82.0 ± 17.5 | 104.9 ± 10.5 | <0.001 | 79.5 ± 17.8 | 100.4 ± 9.6 | <0.001 |
Daily Living | 83.7 ± 12.8 | 103.0 ± 10.2 | <0.001 | 84.0 ± 13.0 | 99.9 ± 10.6 | <0.001 |
Socialization | 80.5 ± 13.0 | 106.3 ± 10.9 | <0.001 | 79.1 ± 9.8 | 99.4 ± 11.0 | <0.001 |
Motor Skills | 87.8 ± 10.9 | 103.1 ± 10.4 | <0.001 | 88.5 ± 10.5 | 98.8 ± 8.5 | <0.001 |
Adaptive Behavior | 80.8 ± 13.0 | 105.0 ± 9.7 | <0.001 | 79.9 ± 11.6 | 99.2 ± 10.3 | <0.001 |
Autism Diagnostic Observation Schedule | ||||||
ADOS SA/CoSo Score | 14.3 ± 3.4 | 2.2 ± 2.0 | <0.001 | 13.3 ± 4.3 | 2.8 ± 1.9 | <0.001 |
ADOS RRB Score | 3.8 ± 1.5 | 0.3 ± 0.6 | <0.001 | 3.1 ± 1.5 | 0.5 ± 0.6 | <0.001 |
ADOS Total Score | 18.1 ± 4.1 | 2.4 ± 2.1 | <0.001 | 16.4 ± 4.7 | 3.3 ± 2.2 | <0.001 |