Table 1 Subjects demographics.

From: A predictive ensemble classifier for the gene expression diagnosis of ASD at ages 1 to 4 years

 

Training set

Test set

 

ASD

TD

ASD vs TD p value

ASD

TD

ASD vs TD p value

Number of Subjects

93

82

0.406

34

31

0.71

Age of last Visit in

50.8 ± 28.8

34.5 ± 8.4

<0.001

47.4 ± 28.0

39.2 ± 15.3

0.144

months

Mullen Scales of Early Learning

 Visual Reception

40.1 ± 13.3

60.3 ± 10.9

<0.001

38.8 ± 15.4

55.1 ± 9.2

<0.001

 Fine Motor

34.8 ± 11.4

54.4 ± 9.5

<0.001

36.9 ± 13.9

52.8 ± 8.9

<0.001

 Receptive Language

32.2 ± 13.1

53.3 ± 8.1

<0.001

29.0 ± 16.6

52.4 ± 7.6

<0.001

 Expressive Language

30.7 ± 15.8

54.4 ± 9.6

<0.001

28.5 ± 16.8

49.8 ± 8.1

<0.001

 Early Learning Composite

73.6 ± 18.5

111.1 ± 13.3

<0.001

71.9 ± 21.0

105.0 ± 11.1

<0.001

Vineland Adaptive Behavior Scales

 Communication

82.0 ± 17.5

104.9 ± 10.5

<0.001

79.5 ± 17.8

100.4 ± 9.6

<0.001

 Daily Living

83.7 ± 12.8

103.0 ± 10.2

<0.001

84.0 ± 13.0

99.9 ± 10.6

<0.001

 Socialization

80.5 ± 13.0

106.3 ± 10.9

<0.001

79.1 ± 9.8

99.4 ± 11.0

<0.001

 Motor Skills

87.8 ± 10.9

103.1 ± 10.4

<0.001

88.5 ± 10.5

98.8 ± 8.5

<0.001

 Adaptive Behavior

80.8 ± 13.0

105.0 ± 9.7

<0.001

79.9 ± 11.6

99.2 ± 10.3

<0.001

Autism Diagnostic Observation Schedule

 ADOS SA/CoSo Score

14.3 ± 3.4

2.2 ± 2.0

<0.001

13.3 ± 4.3

2.8 ± 1.9

<0.001

 ADOS RRB Score

3.8 ± 1.5

0.3 ± 0.6

<0.001

3.1 ± 1.5

0.5 ± 0.6

<0.001

 ADOS Total Score

18.1 ± 4.1

2.4 ± 2.1

<0.001

16.4 ± 4.7

3.3 ± 2.2

<0.001

  1. ADOS autism diagnostic observation schedule, ASD autism spectrum disorder, CoSo communication social score, M/F male/female, RRB restricted and repetitive behavior, SA social affect.