Fig. 1: Genome-wide significant association signals.
From: Genome-wide association study meta-analysis of suicide death and suicidal behavior
Manhattan plots for suicide death GWAS meta-analysis: SNP-level (A), gene-level (B); and suicidal behavior GWAS meta-analysis: SNP-level (C), gene-level (D). Regional plot for NLGN1 (E); regional plot for ROBO2 (F). The dotted line indicates a genome-wide significance threshold of 5 × 10–8. For the regional association plot generated by LocusZoom [95], SNPs in genomic risk loci are color-coded as a function of their r2 to the index SNP in the locus, as follows: red (r2 > 0.8), orange (r2 > 0.6), green (r2 > 0.4) and light blue (r2 > 0.2). SNPs that are not in LD with the index SNP (with r2 ≤ 0.2) are dark blue, while SNPs with missing LD information are shown in gray.
