Table 2 Top genome-wide association signals.

From: Genome-wide association study meta-analysis of suicide death and suicidal behavior

Analysis

CHR

SNP

BP

A1

A2

FRQ_A

FRQ_U

INFO

OR

SE

p

Direction

Nca

Nco

Suicide death

3

rs73182688

173,612,201

A

G

0.885

0.863

0.603

1.06855

0.0122

5.48E–08

++

3765

6572

Suicide death | MDD

          

4.55E–08

   

Suicide death | attempt

          

6.02E–08

   

Suicide death | MDD and attempt

          

4.70E–08

   

Suicidal behavior

3

rs7649370

77,175,484

A

G

0.645

0.677

0.989

1.03448

0.0065

1.51E–07

+++++

8315

256,478

Suicidal behavior | MDD

          

2.89E–07

   

Suicidal behavior

3

rs6782116

77,176,032

C

T

0.651

0.68

0.986

1.03386

0.0065

2.92E–07

–––––

8315

256,478

Suicidal behavior | MDD

          

4.38E–07

   
  1. A1: Allele 1 (odds ratios calculated with respect to this allele), A2: Allele 2, INFO: quality of imputation for the SNP.
  2. BP base-pair position in reference to hg19, CHR chromosome, FRQ_A minor allele frequency (A1) in cases, FRQ_U minor allele frequency (A1) in controls, OR odds ratio, SE standard error, SNP single-nucleotide polymorphism.
  3. SNP in bold reached genome-wide significance threshold in either the main analysis or mtCOJO conditional analysis.
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