Table 1 Socio-demographic and biomarkers data of controls and Long COVID (LC) patients divided into two groups one with highly increased body temperature, lowered SpO2 and high nitro-oxidative stress (LC + O&NS) versus another group with fewer changes in these biomarkers (LC).

Age (years)

30.9 ± 8.3

29.3 ± 7.2

33.1 ± 8.6

3.32

2/151

BMI (kg/m²)

26.34 ± 3.64

25.60 ± 3.97

26.65 ± 6.20

0.72

2/146

Sex (Female/Male)

6/30

25/42

8/43

9.02

2

Education (years)

15.8 ± 1.2^C

15.6 ± 1.6^C

15.5 ± 1.8^A,B

0.37

2/151

Single/married

22/14

34/33

15/36

9.56

2

TUD (No/Yes)

20/16

45/22

36/15

2.24

2

Residency (Urban/Rural)

7/29

7/60

12/39

3.75

2

Employment (No/Yes)

36

67

51

–

–

Vaccination (A/Pf/S)

11/14/11

23/30/14

20/19/12

1.83

4

Duration of Disease (weeks)

–

13.8 ± 3.7^C

15.8 ± 6.8^B

4.16

1/116

Peak body temperature (°C)

36.5 ± 0.1^B,C

38.8 ± .0.1^A,C

39.3 ± 0.1^A,B

163.99

2/142

Lowest SpO2 (%)

96.6 ± 0.6^B,C

92.3 ± 0.4^A,C

87.5 ± 0.5^A,B

70.06

2/142

zTO2 index (z scores)

−1.340 ± 0.091^B,C

0.143 ± 0.070^A,C

0.862 ± 0.079^A,B

170.24

2/142

Gpx (ng/ml)

23.46 ± 0.97^B,C

21.57 ± 0.75^A,C

17.97 ± 0.84^A,B

9.84

2/142

NO (uM)

20.81 ± 1.47^C

18.95 ± 1.13^C

28.19 ± 1.27^A,B

14.99

2/142

Protein carbonyl (ng/ml)

11.38 ± 1.15^C

10.73 ± 0.89^C

14.43 ± 1.00^A,B

3.97

2/142

MPO (ng/ml)

12.87 ± 0.82^C

11.25 ± 0.63^C

15.84 ± 0.71^A,B

11.32

2/142

MDA (nM)

1406.9 ± 97.9^C

1432.9 ± 75.5^C

1843.0 ± 84.6^A,B

8.02

2/142

AOPP (uM)

4.84 ± 0.38

5.27 ± 0.29

5.87 ± 0.33

2.19

2/142

TAC (U/ml)

6.23 ± 0.48

5.23 ± 0.37

5.01 ± 0.41

2.09

2/142

Nitrotyrosine (nM)

33.44 ± 3.20

34.79 ± 2.46

32.72 ± 2.76

0.16

2/142

Zinc (ppm)

0.785 ± 0.034^C

0.772 ± 0.026^C

0.657 ± 0.030^A,B

5.37

2/142

OSTOX (z scores)

−0.357 ± 0.131^C

−0.512 ± 0.101^C

0.882 ± 0.113^A,B

45.19

2/142

ANTIOX (z scores)

0.521 ± 0.151^B,C

0.107 ± 0.116^A,C

−0.580 ± 0.130^A,B

16.17

2/142

OSTOX / ANTIOX (z scores)

−0.575 ± 0.129^A

−0.406 ± 0.100^A

0.957 ± 0.113^A,B

53.62

2/142

CRP (mg/L)

5.42 (0.70)^B,C

7.83 (0.55)^A

9.11 (0.61)^A

7.96

2/140

Enoxaparin sodium (No/Yes)^a

61/6

38/13

5.86

1

Dexamethasone (No/Yes)^a

54/13

27/24

10.29

1

Ceftriaxone (No/Yes)^a

51/16

34/17

1.28

1

Azithromycine (No/Yes)^a

31/36

25/26

0.09

1

Bromhexine (No/Yes)^a

50/17

26/25

7.06

1

Levoflaxacin (No/Yes)^a

61/6

41/10

2.80

1

Antidepressants (No/Yes)^b

55/12

35/16

2.90

1

Chlordiazepoxide (No/Yes)^b

65/2

45/6

FEPT

1

Propanolol (No/Yes)^b

63/4

49/2

0.25

1