Fig. 4: Interactive relationships between LC intensity and plasma markers in predicting PACC performance. | Molecular Psychiatry

Fig. 4: Interactive relationships between LC intensity and plasma markers in predicting PACC performance.

From: Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau

Fig. 4

Note: A effect sizes and 95% confidence intervals of the interaction between each biomarker and the respective LC intensity cluster on PACC performance. The shaded region indicates the best model (ptau231) and this association is depicted in (B). B At values above ~15.7 pg/ml of ptau231, lower LC integrity is associated with lower PACC score.

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