Table 3 Results of association of depression outcomes with dietary sources of metabolites in the UK Biobank.
From: Circulating metabolites modulated by diet are associated with depression
Current depressive symptoms | Lifetime MDD | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Metabolite | Food Proxy | Beta | SE | P-value | N | Beta | SE | P-value | N |
Retinol | Vitamin A supplements | 0.243928 | 0.022056 | 2.00E-28 | 303,274 | 0.351808 | 0.039820 | 1.00E-18 | 189,118 |
Retinol | Retinol intake from food | 0.000227 | 0.000040 | 1.12E-08 | 61,201 | 0.000170 | 0.000055 | 2.14E-03 | 38,648 |
Negative Control | Vitamin D supplements | 0.236158 | 0.015930 | 1.05E-49 | 311,932 | 0.370265 | 0.028033 | 7.87E-40 | 193,957 |
Hippurate | Fresh Fruits | −0.058028 | 0.001966 | 3.29E-191 | 433,153 | −0.035044 | 0.003872 | 1.42E-19 | 263,822 |
Hippurate | Raw Vegetables | −0.028271 | 0.001470 | 2.11E-82 | 430,354 | 0.004597 | 0.002687 | 8.71E-02 | 261,767 |
4-hydroxycoumarin | Vitamin K antagonists | 0.315052 | 0.029455 | 1.07E-26 | 434,232 | 0.054569 | 0.057843 | 3.45E-01 | 264,658 |
mannitol/sorbitol | Artificial sweetener | 0.164990 | 0.017416 | 2.80E-21 | 63,079 | 0.193453 | 0.023738 | 3.65E-16 | 39,829 |
1-linoleoyl-GPA (18:2) | Legumes | −0.063329 | 0.029184 | 3.00E-02 | 63,079 | 0.107547 | 0.040704 | 8.24E-03 | 39,829 |
1-palmitoyl-2-palmitoleoyl-GPC (16:0/16:1) | Eggs | 0.049938 | 0.015835 | 1.61E-03 | 63,079 | 0.052034 | 0.021952 | 1.78E-02 | 39,829 |
