Fig. 3: Drd2 autoreceptor KO mice: predicted social behavior and locomotor activity based on modeled data. | Molecular Psychiatry

Fig. 3: Drd2 autoreceptor KO mice: predicted social behavior and locomotor activity based on modeled data.

From: The human neuropsychiatric risk gene Drd2 is necessary for social functioning across evolutionary distant species

Fig. 3

Data is presented as the logarithm of cumulative time spent sniffing conspecifics in seconds (A), the logarithm of cumulative time spent approach conspecifics in seconds (B) and the logarithm of total distance moved in cm (C) on the Y-axis (mean ± SEM) based on 1-hour bins, with time from the start of the experiment on the X-axis in hours. Autoreceptor knockout animals (n = 7) are shown as the red lines, wildtype animals (n = 7) are shown as blue lines. Yellow shading behind the graph indicates the light phase, where gray shading indicates the dark phase. n = 7; * p < 0,05 based on difference plots after modeling the data with a GAM. (see figures S1-S5 for individual data points and means of observed values).

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