Table 4 The results of Correlation analyses.

From: Systematic reduction of gray matter volume in anorexia nervosa, but relative enlargement with clinical symptoms in the prefrontal and posterior insular cortices: a multicenter neuroimaging study

4-1: Regions of GMV Positively Correlated With EDE-Q Restraint in AN (Corrected for Age and TBV)

Region

P

Cluster size

Peak level

MNI coordinates

t-value

x

y

z

Lt. medial frontal cortex

0.004*

598

−4

50

−12

4.55

4-2: Regions of GMV Positively Correlated With EDE-Q Global Score in AN (Corrected for Age and TBV)

Region

P

Cluster size

Peak level

MNI coordinates

t-value

x

y

z

Lt. medial orbital gyrus

0.014*

1071

−14

51

−15

4.05

Lt. medial frontal cortex

  

−4

48

−12

3.88

Lt. anterior cingulate gyrus

  

0

39

−9

3.70

4-3: Regions of GMV Positively Correlated With EDE-Q Eating Concern Score in AN (Corrected for Age and TBV)

Region

P

Cluster size

Peak level

MNI coordinates

t-value

x

y

z

Rt. posterior insula

0.038*

388

44

−14

0

4.62

4-4: Regions of GMV Positively Correlated With EDE-Q Restraint Score in ANR (Corrected for Age and TBV)

Region

P

Cluster size

Peak level

MNI coordinates

t-value

x

y

z

Rt. posterior insula

0.003*

599

32

−16

8

5.04

  1. *P < 0.05 family-wise error-corrected at cluster level.
  2. AN anorexia nervosa, ANR anorexia nervosa restricting type, EDE-Q Eating Disorder Examination Questionnaire 6.0, GMV gray matter volume, MNI Montreal Neuroimaging Institute, TBV total brain volume.
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