Fig. 2: Associations of PC1 and PC2 with brain structural and cognitive measures. | Molecular Psychiatry

Fig. 2: Associations of PC1 and PC2 with brain structural and cognitive measures.

From: Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition

Fig. 2: Associations of PC1 and PC2 with brain structural and cognitive measures.

Scatter plots for the associations of PC1 (A) and PC2 (B) with global gray matter (GM) volume, global white matter (WM) volume, global white matter hyperintensity (WMH) volume, GM rate of change over follow-ups in AD vulnerable areas (first eigenvariate form PCA, high values denote faster shrinkage), memory performance at baseline and PACC5 change over follow-ups (slope extracted from LME models). Standardized residuals are shown after regressing out covariates (age, gender, p-tau181, Aß42/40 and ICV for brain measures). * denotes significant associations in the full regression models (Tables 2 and 3). CU cognitively unimpaired, CI cognitively impaired.

Back to article page