Table 1 Demographic and clinical characteristics.

From: Age of onset of obsessive-compulsive disorder differentially affects white matter microstructure

 

OCD (N = 260)

HC (n = 252)

Statistics

Sex (N (%))

     Male

117 (45.0%)

105 (41.7%)

χ2(1) = 0.58, P = 0.45

     Female

143 (55.0%)

147 (58.3%)

 Age (years)

29.6 (8.0)

30.0 (8.2)

t(510) = 0.61, P = 0.54

 Education (years)

15.2 (2.8)

16.0 (2.5)

t(510) = 3.52, P < 0.001

 Estimated IQ

104.7 (12.4)

107.1 (12.3)

t(509) = 2.21, P = 0.03

 YBOCS

24.8 (4.9)

0.12 (0.68)

t(510) = −78.7, P < 0.001

 Duration of illnessa

12.3 (8.6)

  

 Age of onset (years)

17.3 (7.1)

 

OCD onset (N (%))a

 Child onset

145 (55.8%)

 

 Adult onset

114 (43.8%)

 

Medication naïve (%)

 SSRI

58.5%

99.2%

 

 SNRI

95.4%

100%

 

 Benzodiazepines

90.4%

99.6%

 

 Antipsychotics

91.9%

99.6%

 

 Mood stabilizers

97.3%

100%

 

 CBT naïve

75.8

100%

 

DYBOCS

 Harm & Aggression

5.3 (4.7)

0.0 (0.4)

 

 Sexual & Religious

4.5 (4.9)

0.0 (0.0)

 

 Symmetry & Ordering

5.7 (4.4)

0.0 (0.2)

 

 Contamination

6.3 (5.0)

0.0 (0.2)

 

 Collecting & Hoarding

1.3 (2.7)

0.0 (0.0)

 
  1. Data are presented as mean (SD) unless otherwise indicated. a = duration of illness/age of onset missing for 1 individual with OCD. YBOCS Yale-Brown Obsessive-compulsive Scale, SSRI selective serotonin reuptake inhibitor, SNRI serotonin-noradrenaline reuptake inhibitor, CBT Cognitive behavioral therapy.