Table 1 Characteristics of cohort participants.
From: Sex effects on DNA methylation affect discovery in epigenome-wide association study of schizophrenia
Cases | Controls | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
ABR | IoPPN | TOP | UCL | Total | ABR | IoPPN | TOP | UCL | Total | |
Sample size | 414 | 290 | 462 | 353 | 1519 | 433 | 203 | 765 | 322 | 1723 |
Sexa | ||||||||||
Male | 283 | 193 | 259 | 254 | 989 | 319 | 113 | 423 | 142 | 997** |
Female | 131 | 97 | 203 | 99 | 530 | 114 | 90 | 342 | 180 | 726 |
Ageb | ||||||||||
Mean (SD) | 47.9 (14.0) | 46.6 (9.6) | 31.3 (10.4) | 43.8 (14.5) | 41.6 (14.2) | 45.2 (12.2) | 30.8 (10.4) | 33.2 (8.7) | 37.6 (14.9) | 36.7 (12.4)** |
Smoking scoresb | ||||||||||
Mean (SD) | 7.4 (6.4) | 8.5 (6.4) | −3.7 (4.4) | 6.7 (6.1) | 4.0 (7.8) | 2.6 (5.3) | 2.4 (4.2) | −5.4 (3.0) | 0.2 (4.7) | −1.4 (5.5)** |
Cell proportion (%)a | ||||||||||
Monocytes | 7.3 | 8.6 | 7.5 | 8.5 | 7.9 | 7.3 | 8.1 | 7.2 | 8.6 | 7.6** |
Granulocytes | 55.8 | 49.6 | 53.7 | 54.2 | 53.6 | 51.7 | 49.6 | 51.2 | 51.0 | 51.1** |
Natural killer cells | 4.8 | 5.8 | 6.6 | 6.4 | 5.9 | 5.0 | 5.8 | 7.3 | 6.7 | 6.5** |
CD4 + T-cells | 15.5 | 17.0 | 20.4 | 18.5 | 18.0 | 17.4 | 16.6 | 20.3 | 18.7 | 18.8** |
CD8 + T-cells | 4.8 | 6.6 | 12.2 | 3.6 | 7.1 | 6.6 | 8.4 | 13.0 | 5.9 | 9.5** |
B-cells | 4.5 | 5.8 | 7.1 | 5.0 | 5.7 | 4.4 | 5.2 | 6.8 | 5.0 | 5.7 |
