Fig. 1: mRNA expression in astrocytes and neurons.
From: Serotonin effects on human iPSC-derived neural cell functions: from mitochondria to depression
mRNA expression of genes involved in A mitochondrial function and dynamics, B neurotransmission and neuronal support, C autophagy and cellular stress and D astrocyte-specific markers and function in serotonin-treated healthy astrocytes relative to untreated astrocytes. E mRNA expression of serotonin receptors 5-HT1A, 5-HT1A and 5-HT3A in untreated neurons relative to untreated astrocytes. mRNA expression of genes involved in F mitochondrial function and dynamics, G neurotransmission and brain function, and H autophagy and cellular stress in serotonin-treated healthy neurons relative to untreated neurons. All cells were derived from Ctl17. Ctl: untreated control. All data were analyzed using unpaired t-tests with Welch’s correction and presented as mean ± SEM. Significant differences were indicated with *p < 0.05, **p < 0.005.
