Table 3 Group differences between HC and MDD patients regarding WM activity, ALFF and ALFF-WM correlation.

From: Aberrant associations between neuronal resting-state fluctuations and working memory-induced activity in major depressive disorder

Anatomical region of group difference

Direction

Cluster size (voxels)

Peak Z-score

MNI peak coordinates

x

y

z

WM task

      

IPL/SPL/poCG/PCU (l)

MDD > HC

203

3.49

−39

−34

52

SPL/PCU (r)

MDD > HC

187

3.83

15

−49

46

ALFF-WM correlation

      

DLPFC (l)

HC > MDD

46

4.23

−33

17

25

PCC/PCU (l & r)

MDD > HC

97

4.54

−12

−49

13

MOG/IOG (r)

MDD > HC

106

4.01

30

−88

4

  1. Cluster-level threshold, p < 0.05 (GRF corrected); uncorrected single-voxel threshold of Z > 2.3. min cluster size WM Task = 141; min cluster size ALFF-WM correlation = 40.
  2. IPL inferior parietal lobule, SPL superior parietal lobule, poCG postcentral gyrus, PCU precuneus, DLPFC dorsolateral prefrontal cortex, PCC posterior cingulate cortex, MOG middle occipital gyrus, IOG inferior occipital gyrus.
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