Fig. 2: Biological context.
From: A meta-analysis of genome-wide studies of resilience in the German population
A Protein-protein interaction network. Input genes were those depicted in Fig. 1C. Linker genes different from the resilience suggested candidates were added to increase network connectivity and interpretability. Successfully integrated input genes are shown in circles. Linker genes are shown in diamonds. Colors represent clusters of genes with high functional interaction scores. Arrows indicate the direction of the interaction, whereas dotted lines indicate predicted interactions. B Network pathways fulfilling criteria for overrepresentation that overlapped input genes. The complete list of overrepresented pathways in the network is available in the Suppl. Table 4. K: KEGG pathway, R: Reactome pathway, N: NCI-Nature pathway.
