Table 2 Correlation between polygenic scores for personality characteristics and RS-11 scores in PROCAM-2.
From: A meta-analysis of genome-wide studies of resilience in the German population
PGS Catalog ID | Phenotype | Method | Publication ID | # PGS SNPs | # Valid SNPs | % Valid SNPs | r | p | FDR |
|---|---|---|---|---|---|---|---|---|---|
PGS001829 | Depression | Penalized regression (bigstatsr) | PGP000263 | 7534 | 7530 | 99.9 | 0.0097 | 0.5453 | 0.5907 |
PGS002213 | Neuroticism | LDpred2 (bigsnpr) | PGP000263 | 950183 | 944901 | 99.4 | −0.0670 | 3.0 × 10−5 | 0.0004 |
PGS002209 | Chronotype | LDpred2 (bigsnpr) | PGP000263 | 955439 | 950000 | 99.4 | −0.0312 | 0.0522 | 0.1131 |
PGS002222 | Self-injurious behavior | LDpred2 (bigsnpr) | PGP000263 | 761279 | 756897 | 99.4 | −0.0170 | 0.2912 | 0.4731 |
PGS002231 | Educational attaintment | LDpred2 (bigsnpr) | PGP000263 | 950845 | 945206 | 99.4 | −0.0333 | 0.0384 | 0.1131 |
PGS002154 | General happinness | LDpred2 (bigsnpr) | PGP000263 | 806011 | 801523 | 99.4 | −0.0505 | 0.0017 | 0.0108 |
PGS001016 | Sensitivity / hurt feelings | snpnet | PGP000244 | 7922 | 7370 | 93.0 | −0.0329 | 0.0405 | 0.1131 |
PGS001017 | Suffer from ‘nerves' | snpnet | PGP000244 | 3348 | 3074 | 91.8 | −0.0224 | 0.1634 | 0.3034 |
PGS001021 | Feelings of worry or anxiety | snpnet | PGP000244 | 9747 | 9110 | 93.5 | −0.0320 | 0.0464 | 0.1131 |
PGS001091 | Loneliness | snpnet | PGP000244 | 660 | 574 | 87.0 | −0.0136 | 0.3965 | 0.5154 |
PGS001398 | Friendship satisfaction | snpnet | PGP000244 | 659 | 590 | 89.5 | 0.0042 | 0.7926 | 0.7926 |
PGS001401 | Health satisfaction | snpnet | PGP000244 | 1814 | 1662 | 91.6 | 0.0110 | 0.4920 | 0.5814 |
