Fig. 2: ASD GWAS and DBD genes. | Molecular Psychiatry

Fig. 2: ASD GWAS and DBD genes.

From: Uncovering convergence and divergence between autism and schizophrenia using genomic tools and patients’ neurons

Fig. 2

A The word cloud of GWAS reported genes associated with ASD. Genes shared with DBD are highlighted in red. Same as Fig. 1A, the font size indicates the frequency of gene mentions in publications, with a larger font size indicating a higher number of reported occurrences. The strongly associated genes have been plotted in Supplementary Fig. 2B. B RNA expression levels of ASD genes across brain anatomical regions. Overlapping genes of GWAS and DBD were used for creating the gene list (n = 30) and the average gene expression level of each brain region was calculated. The “hot” colors represent higher expression levels of the specific brain region and “cold” colors lower expression levels. The graphical image was created with Biorender.com. C Gene network of the common gene list of GWAS and DBD. Color-labeled genes are significantly enriched in either category of Autism (p = 6.82e-19) or Schizophrenia (p = 2.9e-04).

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