Fig. 1: An overview of the study design and principal results from the analyses carried out. | Molecular Psychiatry

Fig. 1: An overview of the study design and principal results from the analyses carried out.

From: A burden of rare copy number variants in obsessive-compulsive disorder

Fig. 1: An overview of the study design and principal results from the analyses carried out.

We have constructed a CNV case/control study using samples from Illumina GSA and its derivatives. We use extensive CNV call quality control to bring our CNV call rate down to around 0.6 per sample. Our principal results all point to a contribution to OCD genetic risk from CNVs that are at least 30 kb in size and a frequency <0.01, at a rate per sample of around 0.07 (95% CI 0.02–0.11, P = 2.58 × 10−3).

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