Table 1 Participant characteristics.

From: Blood biomarkers of neuronal injury and astrocytic reactivity in electroconvulsive therapy

 

ECT participants (N = 99)

Controls (N = 99)

p value

Age, mean (sd)

46.7 (16.1)

42.7 (13.2)

0.089

Female sex

68 (68.7%)

68 (68.7%)

1.000

Diagnosis

 Bipolar depression

15 (15.2%)

  

 Unipolar depression

84 (84.8%)

  

MADRS-S before ECTa, mean (sd)

34.4 (7.4)

  

MADRS-S after ECT, mean (sd)

16.4 (11.0)

  

MADRS-S responseb

56 (58.2%)

  

MADRS-S remission

33 (33%)

  

GSE-My after ECT

3.2 (1.1)

  

Previous history of ECTb

41 (41.4%)

  

Number of ECT sessions, mean (sd)

8.7 (2.5)

  

Treatment parameters at first session

 Bilateral ECT

2 (2.0%)

  

 Pulse width

  0.25–0.49 ms

18 (18.2%)

  

  0.5 ms

67 (67.7%)

  

  0.51–1.0 ms

14 (14.1%)

  

 Electric charge (mC), mean (sd)

255.2 (103.1)

  

 Seizure time (EEG, s), mean (sd)

45 (31–59)

  

Medication before ECT

 Lithium

17 (17.2%)

  

 Valproic acid

3 (3.0%)

  

 Lamotrigine

7 (7.1%)

  

 Second generation antipsychotic

32 (32.3%)

  

 First generation antipsychotic

8 (8.1%)

  

 Antidepressant

84 (84.8%)

  
  1. sd standard deviation, MADRS-S self-rated Montgomery-Åsberg depression rating scale, GSE-My Global Self-evaluation Memory (rated 1–7, lower score indicates worse effect of ECT on memory).
  2. aRating was missing for eight participants.
  3. bData on previous history of ECT was missing for four participants.
  4. P values are from Pearson Chi-square (categorical variables) or Mann–Whitney U-tests (continuous variables).