Fig. 6: CholinotRFs classify female newborns according to maternal PPS. | Molecular Psychiatry

Fig. 6: CholinotRFs classify female newborns according to maternal PPS.

From: Maternal prenatal stress induces sex-dependent changes in tRNA fragment families and cholinergic pathways in newborns

Fig. 6

a–d ROC curves of five marker groups (All DE tRFs, Female DE tRFs, CholinotRFs, All DE miRs, and CholinomiRs), classifying newborns to stress and control groups based on SVM Kernel algorithm with “leave one out” cross validation: (a) females (n = 6 vs. n = 11), (b) males & females (stress vs. control; n = 14 vs. n = 21), (c) males & females (stress-by-sex; n = 14 vs. n = 21), and (d) males (n = 8 vs. n = 10). e Bar plot of AUC values across comparisons with FDR based on 10,000 permutations (available in Supplementary table 9). Created with BioRender.

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