Table 2 Chromosome regions overrepresented with genes related to mental disorders.

From: Deep learning algorithms reveal genomic markers for anxiety disorder in a large cohort of children with down syndrome

Chr locus

Anxiety-specific variation corresponding genes

Anxiety variation genes shared with other mental disorders

chr17q25.3

ARL16, ASPSCR1, CBX2, CBX4, DNAH17, FOXK2, HEXD, NARF, OGFOD3, PVALEF, SLC25A10, SLC38A10, TBCD

ACTG1, AFMID, CANT1, CCDC57, CD7, CEP131, CEP295NL, CSNK1D, CYBC1, CYTH1, DNAH17, FOXK2, GAA, HEXD, LOC100130370, NARF, OGFOD3, RBFOX3, RNF213, RPTOR, SIRT7, SLC16A3, SLC38A10, SOCS3, SYNGR2, TMC6, TMC8, TMEM235

chr16p13.3

ADCY9, CACNA1H, CCDC154, CHTF18, CIAO3, FBXL16, LMF1, MEFV, MMP25, NTHL1, PKD1, PRSS41, RAB26, RGS11, TEDC2, WDR24, ZNF598, ZSCAN32

ADCY9, ALG1, ARHGDIG, BAIAP3, CACNA1H, CAPN15, CASKIN1, CDIP1, CHTF18, CLCN7, CLUAP1, CRAMP1, DECR2, DNASE1, ELOB, FAHD1, FAM234A, FLYWCH1, FLYWCH2, MEFV, MRPL28, NLRC3, NTHL1, OR1F1, OR2C1, PDIA2, PPL, PRR35, PRSS41, RGS11, RNF151, SOX8, SPSB3, SRL, TELO2, TPSD1, TSC2, ZNF598, ZSCAN10, ZSCAN32

chr21q22.3

-

ABCG1, AIRE, CFAP410, COL6A1, DIP2A, FTCD, LRRC3, MX2, PCBP3, PCNT, PRMT2, PTTG1IP, RIPK4, RRP1, RRP1B, SLC19A1, SLC37A1, TRAPPC10, TRPM2, UMODL1

chr22q13.33

-

C22orf34, CRELD2, KLHDC7B, LMF2, MLC1, ODF3B, PLXNB2, SBF1, SHANK3, TUBGCP6

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