Table 1 Baseline characteristics of study participants.

From: Associations between trajectories of plasma biomarkers for Alzheimer’s disease, brain structures, and cognitive function: a prospective cohort study in the UK Biobank

Characteristics

Total sample

Female

Male

P-value*

(n = 1270)

(n = 672)

(n = 598)

Age (years)

59.71 (7.44)

58.88 (6.84)

60.65 (7.97)

<0.001

Education, n (%)

   

0.520

 College or above

641 (50.8)

346 (51.7)

295 (49.7)

 

 Others

629 (49.2)

326 (48.3)

303 (51.3)

 

Townsend deprivation index

−1.57 (2.81)

−1.47 (2.87)

−1.69 (2.74)

0.167

Ethnicity, n (%)

 White

1168 (92.0)

622 (92.6)

546 (91.3)

0.473

 Non-White

102 (8.0)

50 (7.4)

52 (8.7)

 

APOE ε4 carrier, n (%)

257 (20.2)

141 (21.0)

116 (19.4)

0.528

Smoking status, n (%)

   

0.075

 Never

816 (64.7)

450 (67.4)

366 (61.6)

 

 Former

402 (31.9)

199 (29.8)

203 (34.2)

 

 Current

44 (3.5)

19 (2.8)

25 (4.2)

 

Alcohol intake frequency, n (%)

   

<0.001

 Daily or almost daily

199 (15.7)

92 (13.8)

107 (18.0)

 

 3–4 times/week

382 (30.2)

182 (27.2)

200 (33.6)

 

 1–2 times/week

366 (29.0)

193 (28.8)

173 (29.1)

 

 1–3 times/month

149 (11.8)

90 (13.5)

59 (9.9)

 

 Occasions

110 (8.7)

82 (12.3)

28 (4.7)

 

 Never

58 (4.6)

30 (4.5)

28 (4.7)

 

COVID-19, n (%)

636 (50.1)

336 (50.0)

300 (50.2)

0.997

Hypertension, n (%)

645 (50.8)

260 (38.7)

385 (64.4)

<0.001

Diabetes, n (%)

51 (4.0)

15 (2.2)

36 (6.0)

0.001

CAD, n (%)

58 (4.6)

16 (2.4)

42 (7.0)

<0.001

  1. Data are mean (standard deviation), unless otherwise specified.
  2. APOE, apolipoprotein E gene, CAD cardiovascular arterial disease.
  3. *P-value is for the test of differences between males and females.