Fig. 3: Spatial enrichment of individual-level cortical thickness alterations, correlations with clinical scores. | Molecular Psychiatry

Fig. 3: Spatial enrichment of individual-level cortical thickness alterations, correlations with clinical scores.

From: Mapping the path to recovery: the intersection of cortical thickness reductions and serotonin transporter expression in anorexia nervosa

Fig. 3: Spatial enrichment of individual-level cortical thickness alterations, correlations with clinical scores.

We examined whether the individual-level correlation of cortical thickness alterations with the spatial distributions of chemoarchitecture was correlated with clinical symptom severity. BDI-II associations with HT1a and SERT survived FDR correction for multiple comparisons (adjusted p < 0.05), while the association between EDI-2 Body Dissatisfaction and SERT did not. Spearman rho coefficients were corrected for both age and BMI-SDS. Results were computed only within patients. In red negative correlations; in blue positive correlations. Lighter colors indicate weaker correlation, darker colors indicate stronger correlation. BDI-II beck depression inventory, EDI-2 eating disorder inventory 2, DT drive for thinness, BD body dissatisfaction, B Bulimia.

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