Table 2 Genome- and epigenome-wide associations of SNP by cumulative prenatal stress interactions and DNA methylation.
From: Interactive effects of genotype with prenatal stress on DNA methylation at birth
SNP | SNP CHR:BP | CpG | CpG CHR:BP | B (SE) | p | adjusted R2* | direction†| I2 | (nearest) gene SNP‡ | (nearest) gene CpG‡ | SNP-CpG distance (bp) |
|---|---|---|---|---|---|---|---|---|---|---|---|
rs12901653 | 15:93488404 | cg24317086 | 15:93423542 | -0.0262 (0.0032) | 4.067Ă—10-16 | 0.03 | --+ | 93.5 | CHD2 | (CHASERR) | 64,862 |
rs76542426 | 7:103856777 | cg06592260 | 8:144941878 | -0.0128 (0.0017) | 1.12Ă—10-13 | 0.02 | --- | 0.0 | (ORC5) | EPPK1 | 41,085,101 |
rs10279675 | 7:103846781 | cg06592260 | 8:144941878 | -0.0123 (0.0017) | 2.76Ă—10-13 | 0.02 | --- | 0.0 | ORC5 | EPPK1 | 41,095,097 |
rs2188287 | 7:103867883 | cg06592260 | 8:144941878 | -0.0126 (0.0017) | 1.85Ă—10-13 | 0.02 | --- | 0.0 | (ORC5) | EPPK1 | 41,073,995 |
rs10251976 | 7:103834690 | cg06592260 | 8:144941878 | -0.0124 (0.0017) | 7.32Ă—10-13 | 0.02 | --- | 0.0 | ORC5 | EPPK1 | 41,107,188 |