Table 1 Demographic, cognitive and clinical variables by group.

From: Investigating the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences

 

Recent

   

Established

   

Patients

 
 

Controls

Patients

Differencea

Controls

Patients

Differencea

Differenceb

Demographic

Mean (SD)

 

Tr-Diff.

P

Mean (SD)

 

Tr-Diff.

P

Tr-Diff.

P

Age

24.4 (4.4)

24 (5.1)

−0.60

0.521

42.3 (7.8)

42.4 (7.5)

0.28

0.883

19.6

N/A

Parental class (NS-SEC)

2.7 (1.7)

2.9 (1.6)

N/A

0.635

2.9 (1.6)

2.8 (1.8)

N/A

0.721

N/A

0.750

Years of education

16.5 (2.6)

14.7 (2.3)

−2.16

0.001

17 (3.6)

14.5 (3.1)

−2.81

0.001

−0.5

0.377

BMI

24.1 (3.6)

25 (4.4)

0.01

0.988

25.8 (4)

29.8 (5.6)

4.40

0.000

5.4

0.001

Current IQ (FSIQ)

108.9 (22.5)

94.3 (17)

−18.75

0.000

105.2 (16.2)

89.9 (14.2)

−15.17

0.000

−3.5

0.293

Pre-morbid IQ (WTAR)

106.8 (17.5)

100.3 (18.6)

−8.43

0.025

108.4 (9.7)

100 (17.1)

−7.13

0.017

−0.1

0.982

FSIQ-WTAR

−2.1 (14.9)

5.9 (15.3)

−8.83

0.002

3.1 (14.2)

10.1 (14.8)

−7.88

0.011

−5.2

0.054

Clinical

Antipsychotic score

          

AP-day (0–4)

 

0.7 (0.7)

   

1.3 (0.8)

  

0.7

0.000

AP-life (0–10)

 

1.7 (0.8)

   

8 (1.3)

  

6.2

0.000

PANSS Negative

 

14.5 (6.0)

   

13.4 (5.3)

   

0.495c

PANSS Positive

 

12.5 (5.2)

   

13.2 (6.1)

   

0.286c

PSP

 

63.5 (14.2)

   

56.4 (13.5)

  

−8.1

0.011 

  1. Tr-Diff is difference between 20% trimmed means. P values are for Yuen’s robust t-test for differences between trimmed means. NS-SEC p values for the linear-by-linear association χ2 test). P values <0.05 are shown in bold. WTAR and FSIQ values are Standard Scores (pop. Mean = 100, SD = 15)
  2. PSP Personal and Social Performance
  3. aPatient-Control difference
  4. bRecent -Established difference
  5. cp value computed using log10-transformed scores
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