Table 7 Three Biological Processes induced by different treatments with ECs.
Group | Top 5 Canonical Pathways | |
|---|---|---|
Name | p-value range | |
VEH ECs | RNA Pol III Transcription | 1.25E-04 |
Assembly of RNA Pol III Complex | 6.19E-03 | |
mRNA Capping | 1.19E-02 | |
Nucleotide Excision Repair Pathway | 1.44E-02 | |
Nucleosome assembly | 2.01E-02 | |
VEH | SIV ECs | Metabolism of vitamin K | 5.29E-03 |
PI Metabolism | 9.47E-03 | |
Xanthine and Xanthosine Salvage | 1.06E-02 | |
Cell Cycle Checkpoints | 1.50E-02 | |
Guanine and Guanosine Salvage | 1.58E-02 | |
THC | SIV ECs | PI Metabolism | 2.49E-03 |
Mitotic Roles of Polo-Like Kinase | 7.25E-03 | |
Cilium Assembly | 8.51E-03 | |
NAD Phosphorylation and Dephosphorylation | 9.32E-03 | |
Gamma carboxylation, hypusine formation and arylsulfatase activation | 1.14E-02 | |
Top 5 Diseases and Biological Functions | ||
VEH ECs | Name | p-value range |
Connective Tissue Disorders | 4.14E-04 - 4.14E-04 | |
Developmental Disorder | 4.14E-04 - 4.14E-04 | |
Hereditary Disorder | 2.21E-02 - 4.14E-04 | |
Organismal Injury and Abnormalities | 4.80E-02 - 4.14E-04 | |
Skeletal and Muscular Disorders | 2.13E-02 - 4.14E-04 | |
VEH | SIV ECs | Neurological Disease | 4.92E-02 - 5.77E-07 |
Organismal Injury and Abnormalities | 4.92E-02 - 5.77E-07 | |
Cancer | 4.92E-02 - 3.41E-06 | |
Dermatological Diseases and Conditions | 4.67E-02 - 5.75E-04 | |
Gastrointestinal Disease | 4.67E-02 - 9.10E-04 | |
THC | SIV ECs | Cancer | 4.49E-02 - 7.36E-17 |
Organismal Injury and Abnormalities | 4.49E-02 - 7.36E-17 | |
Gastrointestinal Disease | 4.27E-02 - 1.10E-13 | |
Endocrine System Disorders | 4.42E-02 - 4.83E-10 | |
Neurological Disease | 4.49E-02 - 1.14E-07 | |
Top 5 Molecular and Cellular Functions | ||
Name | p-value range | |
VEH ECs | Cell Death and Survival | 3.54E-02 - 4.14E-04 |
Cellular Assembly & Organization | 2.74E-02 - 4.14E-04 | |
DNA Replication, Recombination, Repair | 2.13E-02 - 4.14E-04 | |
Small Molecule Biochemistry | 2.13E-02 - 8.27E-04 | |
Cell Cycle | 2.74E-02 - 1.24E-03 | |
VEH | SIV ECs | Cell Death and Survival | 4.25E-02 - 5.77E-07 |
Cell Morphology | 4.67E-02 - 5.77E-07 | |
Cellular Compromise | 3.13E-02 - 5.77E-07 | |
Cellular Assembly and Organization | 4.67E-02 - 1.77E-03 | |
Cellular Function and Maintenance | 4.67E-02 - 1.77E-03 | |
THC | SIV ECs | Cell Morphology | 4.49E-02 - 1.30E-04 |
Cell Death and Survival | 4.49E-02 - 6.51E-04 | |
Cellular Assembly and Organization | 4.49E-02 - 1.10E-03 | |
Cellular Function and Maintenance | 4.49E-02 - 1.10E-03 | |
Carbohydrate Metabolism | 4.49E-02 - 1.89E-03 | |
