Fig. 7: The computational model of Brainquake for the psychotic brain.

The model of the psychotic brain suggests greater instability in several key brain networks (sensorimotor, visual, temporal, default mode, and fronto-parietal networks, as well as in the hippocampal and amygdalar regions) compared to the normal brain. The concept of Brainquake, inspired by earthquakes, compares certain unstable brain networks to active volcanoes, which are more prone to eruption than those in a normal brain. To aid in the recognition of brain regions on the flat brain surface, reference lines are labeled to define the inner and outer boundaries of the insula (Ins) and the central sulcus (CS). Additional key landmarks include the dorsolateral prefrontal cortex (DLPFC), posterior parietal cortex (PPC), rostral lateral temporal cortex (rLTC), posteromedial cortex (PMC), parahippocampal cortex (PHC), and medial prefrontal cortex (MPFC).